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Genomics: Essential Methods by Mike Starkey, Ramnath Elaswarapu PDF

By Mike Starkey, Ramnath Elaswarapu

ISBN-10: 0470711574

ISBN-13: 9780470711576

Genomics learn has made major advances lately. during this publication, a workforce of internationally-renowned researchers proportion the main updated details in a box that has in recent times switched emphasis from gene identity to sensible genomics and the characterization of genes and gene items. This quantity ways this advanced topic with a extensive point of view to provide the reader with an important review of genomics and its spinoff fields, with a spotlight on pivotal matters corresponding to information research. Expansive and current, this book is a accomplished study consultant that describes either the foremost new thoughts and extra validated tools. each bankruptcy discusses the benefits and obstacles of a few of the ways after which offers chosen tried-and-tested protocols, in addition to a plethora of excellent functional suggestion for instant use on the bench.

Key features:

  • Provides a huge advent to present practices and methods for lab-based study in genomics
  • Explains in actual fact and accurately find out how to perform chosen suggestions as well as heritage info at the quite a few approaches
  • Chapters are written through a number one overseas professionals within the box and canopy either famous and new, attempted and demonstrated, equipment for operating in genomics
  • Includes troubleshooting consultant and reports of other techniques
  • An crucial laboratory guide for college students and researchers in any respect levels

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Genomics study has made major advances lately. during this ebook, a staff of internationally-renowned researchers percentage the main up to date info in a box that has lately switched emphasis from gene id to practical genomics and the characterization of genes and gene items.

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Additional resources for Genomics: Essential Methods

Sample text

2005) High-resolution analysis of chromosomal imbalances using the Affymetrix 10K SNP genotyping chip. Genomics, 85, 392–400. 31. H. X. (2005) Quantile smoothing of array CGH data. Bioinformatics, 21, 1146–1153. 32. , Pals, G. et al. (2002) British Journal of Cancer, 87, 892–897. 33. , Tang, W. et al. (2006) Molecular diagnosis of Prader–Willi and Angelman syndromes by methylation-specific melting analysis and methylation-specific multiplex ligation-dependent probe amplification. Clinical Chemistry, 52 (7), 1276–1283.

J. et al. (2000) Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays. Nature Biotechnology, 18, 1001–1005. 17. , Zhao, X. et al. (2004) High-resolution single-nucleotide polymorphism array and clustering analysis of loss of heterozygosity in human lung cancer cell lines. Oncogene, 23, 2716–27262. 18. G. et al. (2004) An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays. Cancer Research, 64, 3060–3071.

2004) Nature Genetics, 36, 299–303. 10. A. et al. (1999) Genome-wide analysis of DNA copy-number changes using cDNA microarrays. Nature Genetics, 23, 41–46. 11. , Carvalho, B. et al. (2007) Resolving the resolution of array CGH. Genomics, 89, 647–653. Interesting paper on algorithms dealing with the resolution of diverse microarray CGH platforms. 12. , Paeslack, U. et al. (2000) Quantitation of DNA extracted after micropreparation of cells from frozen and formalin-fixed tissue sections. American Journal of Pathology, 156, 1189–1196.

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Genomics: Essential Methods by Mike Starkey, Ramnath Elaswarapu

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