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Functional MRI: Basic Principles and Clinical Applications - download pdf or read online

By Seong-Gi Kim PhD, Peter A. Bandettini PhD (auth.), Scott H. Faro MD, Feroze B. Mohamed PhD (eds.)

ISBN-10: 0387230467

ISBN-13: 9780387230467

ISBN-10: 0387346651

ISBN-13: 9780387346656

Scott H. Faro and Feroze B. Mohamed have succeeded in translating benchmark examine on sensible MRI into medical functions for the healthcare professional and cognitive neuroscientist, delivering these unusual with fMRI physics with a lot wanted history. This useful and well timed quantity provides an outline of the foundations of fMRI and explains key strategies, together with scanning methodologies, experimental examine layout, and information research. Informative discussions disguise the technical and scientific demanding situations linked to fMRI. A neuroanatomical atlas provides to the practical method and serves as an invaluable reference by way of basically illustrating basic functioning for vital components of the mind. the ultimate element of the publication is dedicated to basic medical purposes of fMRI in motor, sensory, language, cognitive, and pharmacology. A concluding bankruptcy addresses destiny functions. individuals to this accomplished quantity comprise across the world well-known neuroradiologists, neurologists, psychiatrists, cognitive neuroscientists, and physicists. A wealth of four-color illustrations completes this crucial text.

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Additional resources for Functional MRI: Basic Principles and Clinical Applications

Example text

It typically is achieved by an augmentation of the static magnetic field B0 with a set of supplemental magnetic fields, gradient fields, with known, and usually linear, spatial profiles. Such magnetic fields are a special kind of inhomogeneity that make spin precessional frequency position-dependent in a known fashion. 1), taking into consideration the gradient amplitude. 2) where the amplitude of the applied gradient Gz is given as the spatial partial derivative of the gradient field BG. 3) ∂BG ˆ Ê w(y) = g (B0 + BGy ) = g (B0 + Gy y) = g B0 + y .

Functional magnetic resonance imaging of the human brain. J Neurosci Methods. 1997;74:229–243. 52. Stejskal EO, Tanner JE. Spin diffusion measurements: Spin echoes in the presence of a time-dependent field gradient. J Chem Physics. 1965;42: 288–292. 53. Song AW, Wong EC, Tan SG, Hyde JS. 5 T. Magn Reson Med. 1996;35:155–158. 54. Zhong J, Kennan RP, Fulbright RK, Gore JC. Quantification of intravascular and extravascular contributions to BOLD. Magn Reson Med. 1998;40:526–536. 55. Duong TQ, Yacoub E, Adriany G, Hu X, Ugurbil K, Kim S-G.

Because only the in-plane displacement alters relaxation rates, the corrected expression for the average displacement is now L2 = 4Dt. 12) Taking t = 100 milliseconds, a typical echo time in case of the spin-echo pulse sequence, the average displacement is estimated at 20 micrometers. It is therefore expected that the effect of diffusion in areas of venulae larger than 20 micrometers in diameter gradually diminishes reversely proportional to the venule’s size. This is due to the fact that the spinecho is refocused relatively better because the water molecule spends more time in the same field.

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Functional MRI: Basic Principles and Clinical Applications by Seong-Gi Kim PhD, Peter A. Bandettini PhD (auth.), Scott H. Faro MD, Feroze B. Mohamed PhD (eds.)


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