By Judith Campbell, and Paul Modrich (Eds.)
This quantity offers particular assurance of recent equipment for molecular research of enzymes and enzyme platforms that functionality within the upkeep of genome integrity. insurance parts contain base excision fix, nucleotide excision fix, translesion DNA polymerases, mismatch fix, genetic recombination, and double strand holiday fix.
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*Part A of a 2-part sequence
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Extra info for DNA Repair, Part A
Decline of nuclear and mitochondrial oxidative base excision repair activity in late passage human diploid fibroblasts. DNA Repair 2, 673–693. , and Krokan, H. E. (2003). The interacting pathways for prevention and repair of oxidative DNA damage. Mutat. Res. 531, 231–251. , Latham, K. , Dodson, M. , and Lloyd, R. S. (1995). Studies on the catalytic mechanism of five DNA glycosylases: Probing for enzyme‐DNA amino intermediates. J. Biol. Chem. 270, 19501–19508. Verdine, G. , and Norman, D. P. (2003).
2000). A single engineered point mutation in the adenine glycosylase MutY confers bifunctional glycosylase/AP lyase activity. Biochemistry 39, 10098–10109. Wilson, D. , 3rd, Sofinowski, T. , and McNeill, D. R. (2003). Repair mechanisms for oxidative DNA damage. Front. Biosci. 8, d963–d981. , Chaudhry, M. , and Wallace, S. S. (2005). Base excision repair by hNTH1 and hOGG1: A two–edged sword in the processing of DNA damage in ‐irradiated human cells. DNA Repair. , and Wallace, S. S. (2004). Attempted base excision repair of ionizing radiation damage in human lymphoblastoid cells produces lethal and mutagenic double strand breaks.
Krokan, H. , and Slupphaug, G. (2000). Base excision repair of DNA in mammalian cells. FEBS Lett. 476, 73–77. Krokan, H. , and Slupphaug, G. (1997). DNA glycosylases in the base excision repair of DNA. Biochem. J. 325, 1–16. , and Sarasin, A. (2000). Transcription coupled repair of 8‐oxoguanine in murine cells: The ogg1 protein is required for repair in nontranscribed sequences but not in transcribed sequences. Proc. Natl. Acad. Sci. USA 97, 8397–8402. , Clark, R. , and Roy, A. K. (2000). Role of redox‐regulated transcription factors in inflammation, aging and age‐related diseases.
DNA Repair, Part A by Judith Campbell, and Paul Modrich (Eds.)