By Lisa Yount
This e-book profiles the lifestyles and occupation of Craig Venter, who in 1998 introduced that his deepest corporation could map the complete human genetic series.
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Additional info for Craig Venter: Dissecting the Genome
Smith proposed one: sequencing the genome of Hemophilus influenzae, the bacterium in which he had discovered his first restriction enzyme. indd 38 9/16/11 11:07 AM Spelling Out the Code 39 Nobel Prize–winner Hamilton Smith, shown here, helped Craig Venter sequence many kinds of genomes, beginning with bacteria. The two men also became lifelong friends. In the late 2000s, Smith led a project that was attempting to synthesize a living microorganism from inert chemicals. (J. Craig Venter Institute) does not cause influenza.
The new institute, Venter and Steinberg agreed, would be called The Institute for Genomic Research. Venter insisted that the T in the be capitalized, so that the abbreviation for the institute would be TIGR—pronounced tiger. Craig Venter planned to make sure that before long, all of bioscience would hear his “tiger” roar. indd 35 9/16/11 11:07 AM 3 Spelling Out the Code Craig Venter was thrilled to have what most scientists could only dream of: his own institute, almost unlimited funding for it—Steinberg promised him $10 million to start and another $60 million to be spread over the following 10 years—and a substantial sum in his own pocket.
The DNA strands moved down the gel, with the shorter strands traveling faster and the longer ones moving more slowly, so this process, called electrophoresis, sorted the strands by size. When the process was complete, Sanger exposed the gel to film, on which the radioactive false bases left dark spots. Technicians noted the location of the spots in the four different tracks and used this information to determine the sequence of bases in the original DNA strand. indd 22 9/16/11 11:07 AM Fishing for Genes 23 DREAMING OF THE HUMAN GENOME While Craig Venter and his laboratory mates were struggling to find and sequence their receptor gene, a few farsighted scientists were beginning to envision a far more ambitious task: determining the sequence of bases in the entire genome of a human being, which contains several billion base pairs.
Craig Venter: Dissecting the Genome by Lisa Yount