By J. Victor Small, Klemens Rottner (auth.), Marie-France Carlier (eds.)
This booklet provides the mobile, molecular and actual features of strength and circulate through the self-assembly of actin, probably the most plentiful proteins present in cells, into cytoskeletal filaments. « Actin-based motile techniques » are chargeable for a wide number of motile actions akin to chemotactic locomotion, embryonic and metastatic phone migration, wound therapeutic, eukaryotic cytokinesis and bacterial plasmid segregation, endocytic and phagocytic actions, in addition to morphogenetic methods together with, axis patterning in early embryos, axonal progress in mind improvement, and the immune reaction and synaptic plasticity techniques on the starting place of studying and reminiscence. The publication describes how the lately undertaken multidisciplinary and multiscale techniques have explored the molecular and actual mechanisms on the starting place of strength and move produced via actin self-assembly. the selected issues convey how advances were made within the box of telephone motility as a result of the development in stay phone imaging, gentle microscopy, more advantageous answer within the constitution of enormous protein assemblies, the biochemical research and mathematical modeling of actin meeting dynamics and the improvement of nanotechnologies permitting us to degree forces within the diversity of pico- to nano-newtons produced through actin assemblies.
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Extra info for Actin-based Motility: Cellular, Molecular and Physical Aspects
A Variety of Plasma Membrane Invaginations . . . . . . . . . Membrane Deformation by the BAR and EFC/F-BAR Domains . . . . . The BAR and EFC/F-BAR Domain-Containing Proteins are Connected to the actin Cytoskeleton Through N-WASP . . . . . . 5 IMD/I-Bar Domain Induces Outward Protrusions . . . . . . . . 6 Direction of Actin Polymerization Beneath the Membrane . . . . . . 7 Membrane Curvature-Dependent Actin Polymerization .
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Actin-based Motility: Cellular, Molecular and Physical Aspects by J. Victor Small, Klemens Rottner (auth.), Marie-France Carlier (eds.)