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By Andrej Čretnik

ISBN-10: 9535102648

ISBN-13: 9789535102649

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Briefings in bioinformatics, 3: 146-153. Maffulli N, Reaper JA, Waterston SW, and Ahya T. (2000). ABO blood groups and achilles tendon rupture in the Grampian Region of Scotland. Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, 10: 269-271. Magra M and Maffulli N. (2007). Genetics: Does it play a role in tendinopathy?. Clinical Journal of Sports Medicine 17 (4), 231-233. Malfait F, Wenstrup, R. , & De Paepe, A. (2010). Clinical and genetic aspects of EhlersDanlos syndrome, classic type.

1 The COL5A1 3’-UTR is functional and associated with other exercise-related phenotypes Although a genetic association of a sequence variant (rs12722) within the COL5A1 3’-UTR has previously been reported for chronic Achilles tendinopathy (Mokone et al, 2006; September et al, 2009) in two independent populations, the biological function, if any, of the COL5A1 3’-UTR was initially unknown. , 2003). In addition variant rs12722 within the COL5A1 3’UTR is in close proximity with two polymorphic putative miRNA binding sites within the COL5A1 3’-UTR (September et al, 2009).

2011). Regulation of gene expression in human tendinopathy. BMC Musculoskeletal Disorders 12: 86. Jones FS, and Jones PL. (2000). The tenascin family of ECM glycoproteins: structure, function, and regulation during embryonic development and tissue remodeling. Developmental Dynamics 218: 235-259. Jozsa L, Balint JB, Kannus P, Reffy A, and Barzo M. (1989). Distribution of blood groups in patients with tendon rupture. An analysis of 832 cases. The Journal of bone and oint surgery. British volume, 71: 272-274.

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Achilles Tendon by Andrej Čretnik

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