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A Computer Scientist's Guide to Cell Biology by William W. Cohen PDF

By William W. Cohen

ISBN-10: 038748275X

ISBN-13: 9780387482750

This booklet is designed in particular as a advisor for desktop Scientists wanting an advent to telephone Biology. The textual content explores 3 varied aspects of biology: organic platforms, experimental tools, and language and nomenclature. the writer discusses what biologists are attempting to figure out from their experiments, how a number of experimental approaches are used and the way they relate to approved innovations in desktop technology, and the vocabulary essential to learn and comprehend present literature in biology. The booklet is a useful reference device and a very good start line for a extra finished exam of phone biology.

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Extra resources for A Computer Scientist's Guide to Cell Biology

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William W. Cohen 41 Remarkably, it is now possible to create fluorescent dyes that are extremely specific—dyes that will bind themselves to only a few particular proteins in a cell—and use these dyes to visualize the behavior of specific proteins inside a cell. We will discuss two ways of doing this below, in the sections on antibodies and the section on fusion proteins. Figure 24 shows some sample images from a fluorescent microscope. In this experiment, researchers were studying the behavior of a certain type of receptor protein called the HT-52A receptor, which is sensitive to a number of familiar substances including LSD, psilocin, and mescaline.

William W. Cohen E 43 F Electron microscope images. (A) human HeLa cells (B) the inset in (A), further magnified. (C) hamster CHO cells, with some mitochondria shown in the inset. (D) actin filiments. (E) part of the intestinal cell of a 4-day old rat. (F) the vesicle indicated with an arrow in (E). Scale bars are 1 micrometer in E, 100 nm in F. Figure 25. Electron microscope images. Manipulation of the Very Small Taking small things apart A well-worn cliché is that cells are machines, the components of which are molecules.

Hence, if one wishes to visualize objects deep inside a cell, it is necessary to cut it into thin sections—which in turn requires extensive preparation, usually including dehydrating the cell and then allowing resin to permeate into it, or freezing the cell very rapidly. , gold. Both of these procedures (to put it moderately) tend to cause damage, so preserving a specimen in something like its native state is often a major challenge for electron microscopy. Work on using electron microscopes in close-to-normal conditions is an active area of research, however.

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A Computer Scientist's Guide to Cell Biology by William W. Cohen


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